If you're going to be spending a lot of time with your baby, it's gotta feel right. You've mentioned having smaller hands. The neck is going to be a big factor with regard to width, shape, and finish. Angus Young prefers the SG for the sound and also the smaller neck, which is a perfect fit for his smaller hands. Strats, for instance, come with several different neck shapes and each player is going to have his or her own preference. Some you might find are exhausting to play, whereas others feel effortless. The type of wood used for the body can factor in on the weight of the guitar as well. Les Pauls tend to be a bit heavy, whereas Strats, SGs, and Ibanez guitars are lighter in weight. Ergonomics are a factor as well. Also, there is a distinctive difference in the sound and tone of say, a Strat versus a Les Paul, although these days with so many different brands of pickups and amps, you could tweak your sound. Then, there's the mojo factor: do both you and the guitar seem to come alive when you're playing it? What might seem right on paper and practicality doesn't hold a candle to the way it feels in your hands and what happens when you start playing. So by all means, don't narrow down your options too much.
Prices can vary considerably. Often when it comes to guitars, you get what you pay for--but not always! There are some real gems out there that can be had for a fraction of some of the others. Stevie Ray Vaughan found his beat-up, though beloved Number One in a pawn shop. Keep in mind, too, that if you find one that feels great in your hands and is comfortable to play, you can always change the pickups, the color, etc.
Perhaps pay a visit to a pawn shop or music store and just try out several different ones, noting what feels good to you, what is comfortable, what really wows you. Something out there might be love at first sight (and sound) for you.
Good luck in your search--and by all means, have fun with it!